Amino Acids And Brain Function

Cognitive function [among other things] is influenced by the availability and metabolism of amino acids.

This graphic is meant to highlight the multifaceted roles of specific amino acids in neural pathways.

For instance, β-alanine stands as a neuromodulator with affinities for GABA and glycine receptors, intricately involved in synaptic responses. L-arginine, a precursor for nitric oxide, plays a pivotal role in synaptic plasticity by regulating neurotransmitters like glutamate and dopamine.

L-histidine’s metabolism to histamine underscores its impact on alertness and the sleep/wake cycle, while L-leucine’s influence on hunger signaling and brain energy metabolism links metabolic states to cognitive functions. L-serine’s contribution to neurotransmission through the production of D-serine, a co-agonist of the NMDA receptor, demonstrates the direct involvement of amino acids in modulating synaptic plasticity. L-tryptophan’s metabolism to serotonin and melatonin ties its dietary intake directly to mood and sleep regulation.

Again, cognitive function [among other things] is influenced by the availability and metabolism of amino acids. This underscores the necessity of a well-rounded diet for maintaining vital cognitive functions. The sources of these amino acids – ranging from meats to dairy, legumes, and nuts – provide a roadmap for dietary strategies aimed at enhancing cognitive function and mental health.